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L-Dihydroorotic acid

CAS No. 5988-19-2

L-Dihydroorotic acid ( —— )

产品货号. M19640 CAS No. 5988-19-2

L-二氢乳清酸,也称为(S)-4,5-二氢乳清酸盐或二氢-L-乳清酸盐,属于称为α氨基酸及其衍生物的有机化合物类别。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG ¥316 有现货
500MG ¥770 有现货
1G ¥1150 有现货

生物学信息

  • 产品名称
    L-Dihydroorotic acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    L-二氢乳清酸,也称为(S)-4,5-二氢乳清酸盐或二氢-L-乳清酸盐,属于称为α氨基酸及其衍生物的有机化合物类别。
  • 产品描述
    L-Dihydroorotic acid also known as (S)-45-dihydroorotate or dihydro-L-orotate belongs to the class of organic compounds known as alpha amino acids and derivatives. Within the cell L-dihydroorotic acid is primarily located in the cytoplasm and mitochondria. L-Dihydroorotic acid exists in all eukaryotes ranging from yeast to humans. L-Dihydroorotic acid participates in a number of enzymatic reactions. In particular L-Dihydroorotic acid can be biosynthesized from ureidosuccinic acid; which is catalyzed by the enzyme cad protein. In addition L-Dihydroorotic acid and quinone can be converted into orotic acid; which is mediated by the enzyme dihydroorotate dehydrogenase (quinone) mitochondrial. In humans L-dihydroorotic acid is involved in the pyrimidine metabolism pathway. L-Dihydroorotic acid is also involved in several metabolic disorders some of which include UMP synthase deficiency (orotic aciduria) the mngie (mitochondrial neurogastrointestinal encephalopathy) pathway Beta ureidopropionase deficiency and dihydropyrimidinase deficiency.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    5988-19-2
  • 分子量
    158.11
  • 分子式
    C5H6N2O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:196.1 mM
  • SMILES
    OC(=O)[C@@H]1CC(=O)NC(=O)N1
  • 化学全称
    (S)-26-dioxohexahydropyrimidine-4-carboxylic acid

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Jiang G. et al.: J. Med. Chem. 44 453 (2001)
产品手册
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